3-[2-Cyclopropyl-4-(4-fluorophenyl)-3- quinolyl]prop-2-enal of the below formula (see above formula) is prepared in a high yield by reducing 3-[2-cyclopropyl-4- (4-fluorophenyl)-3-quinolyl]prop-2-enenitrile with Raney nickel either in the presence of formic acid and 0.25 to 1 part by volume of water per part by volume of formic acid or in the presence of both an amine salt of formic acid and an organic acid.
申请公布号
CA2398138(C)
申请公布日期
2009.12.22
申请号
CA20012398138
申请日期
2001.01.24
申请人
NISSAN CHEMICAL INDUSTRIES, LTD.;UBE INDUSTRIES, LTD.