STABLE OPHTHALMICAL COMPOSITION COMPRISING KETOTIFEN AND NAPHAZOLINE AND METHODS OF MAKING SAME.

摘要

Stable compositions comprising ketotifen or a ketotifen salt and methods of preparing such compositions are provided. The pH of the compositions remains at less than about 5 during storage. The methods comprise preparing pharmaceutical compositions comprising ketotifen or a ketotifen salt, and adjusting their pH to less than 5, thus slowing the changes of the active ingredients.