| 发明名称 |
TLR4 decoy receptor protein |
| 摘要 |
The present application discloses a nucleic acid molecule encoding a fusion polypeptide capable of binding myeloid differentiation protein-2 (MD-2) polypeptide, which includes: a nucleotide sequence encoding an MD-2 polypeptide-binding portion of human toll-like receptor 4 (TLR4), a leucine-rich repeats (LRR) module, and a multimerizing component.
|
| 申请公布号 |
US2009312249(A1) |
申请公布日期 |
2009.12.17 |
| 申请号 |
US20080315989 |
申请日期 |
2008.12.08 |
| 申请人 |
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY |
发明人 |
JUNG KEEHOON;KIM HOMIN;KIM HAK-ZOO;LEE JUNG-EUN;LEE GYUN MIN;KIM SUN CHANG;LEE JIE-OH;KIM HAK-SUNG;KOH GOU YOUNG |
| 分类号 |
A61K38/17;A61P29/00;A61P31/04;C07K14/47;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12N15/74;C12N15/85;C12P21/04 |
主分类号 |
A61K38/17 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
