发明名称 |
COMPOUNDS FOR THE TREATMENT OF AURICULAR FIBRILLATION |
摘要 |
Adenosine A2A receptor antagonists are useful for the preparation of medicaments against atrial fibrillation in mammals, including humans. It has been found that the adenosine A2A receptor is present in human atrial cardiomyocytes and participates in the pathological mechanisms underlying atrial fibrillation. An advantage of using A2A antagonists over other agents known in the art is that the A2A antagonists specifically target patients with atrial fibrillation.
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申请公布号 |
US2009312332(A1) |
申请公布日期 |
2009.12.17 |
申请号 |
US20060090115 |
申请日期 |
2006.10.10 |
申请人 |
PROYECTO DE BIOMEDICINA CIMA, S.L. |
发明人 |
FRANCO FERNANDEZ RAFAEL;CIRUELA ALFREZ FRANCISCO;LLUIS BISET CARMEN;MUELLER CHRISTA;CINCA CUSCULLOLA JOAN;HOVE-MADSEN LEIF |
分类号 |
A61K31/519;A61K31/4985;A61K31/522;A61K31/53 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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地址 |
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