In accordance with an aspect of the invention, implantable or insertable medical devices are provided that comprise (a) a substrate and (b) a porous layer comprising close packed spherical pores disposed over the substrate. The porous layer may also comprise a therapeutic agent. In another aspect, the present invention provides methods of forming implantable or insertable medical devices. These methods comprise forming a predecessor structure that comprises (i) a substrate over which is disposed (ii) an assembly of microspheres. This assembly of microspheres is then used as a template for the formation of a porous layer, which may be subsequently loaded with a therapeutic agent.
申请公布号
WO2009018035(A3)
申请公布日期
2009.12.17
申请号
WO2008US70842
申请日期
2008.07.23
申请人
BOSTON SCIENTIFIC SCIMED, INC.;ATANASOSKA, LILIANA;WARNER, ROBERT, W.;ARNEY, MICHAEL, S.;WEBER, JAN
发明人
ATANASOSKA, LILIANA;WARNER, ROBERT, W.;ARNEY, MICHAEL, S.;WEBER, JAN