| 发明名称 |
EXPRESSION OF O-GLYCOSYLATED THERAPEUTIC PROTEINS IN PROKARYOTIC MICROORGANISMS |
| 摘要 |
The invention relates to methods of producing an O-glycosylated soluble therapeutic protein in a prokaryotic microorganism by co-expressing the therapeutic protein and a heterologous glycosyltransferase that transfers a sugar moiety to an amino acid acceptor on the therapeutic protein.
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| 申请公布号 |
US2009311744(A1) |
申请公布日期 |
2009.12.17 |
| 申请号 |
US20070297488 |
申请日期 |
2007.04.19 |
| 申请人 |
DEFREES SHAWN;SCHWARTZ MARC F;JOHNSON KARL |
发明人 |
DEFREES SHAWN;SCHWARTZ MARC F.;JOHNSON KARL |
| 分类号 |
C12P21/06;C12N1/21 |
主分类号 |
C12P21/06 |
| 代理机构 |
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