发明名称 |
Annelated N-heterocyclic sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals |
摘要 |
<p>Annelated N-heterocyclic sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals The invention relates to annelated N-heterocyclic sulfonamides with oxadiazolone headgroup and to their physiologically acceptable salts and physiologically functional derivatives showing PPARdelta or PPARdelta and PPARalpha agonist activity. What is described are compounds of the formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.</p> |
申请公布号 |
AU2009256982(A1) |
申请公布日期 |
2009.12.17 |
申请号 |
AU20090256982 |
申请日期 |
2009.05.22 |
申请人 |
SANOFI-AVENTIS |
发明人 |
MAIKE GLIEN;EUGEN FALK;MATTHIAS URMANN;STEFANIE KEIL;WOLFGANG WENDLER;HANS MATTER |
分类号 |
C07D413/10;A61K31/436;A61K31/4706;A61K31/4709;A61K31/5365;A61K31/5383;A61P3/00;A61P25/00;C07D413/12;C07D413/14;C07D417/10;C07D471/04;C07D498/04 |
主分类号 |
C07D413/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|