发明名称 |
METHOD FOR PRODUCING HYDRAZONE COMPOUNDS |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for commercially advantageously producing a hydrazone compound useful as an intermediate for producing medicines. Ž<P>SOLUTION: L-rhamnose diethylmercaptal is reacted with hydrogen peroxide in the presence of tungstic acid and phospho-oxo acid to obtain a dialkylsulfonylmethane derivative. The derivative is reacted with a hydrazine compound to produce the hydrazone derivative of formula (4) wherein, R<SP>3</SP>is H or OH; R<SP>4</SP>, R<SP>5</SP>are each H, an alkyl group or an aryl group. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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申请公布号 |
JP2009292726(A) |
申请公布日期 |
2009.12.17 |
申请号 |
JP20060249156 |
申请日期 |
2006.09.14 |
申请人 |
SHIRATORI PHARMACEUTICAL CO LTD;ASUBIO PHARMA CO LTD |
发明人 |
TAZAWA SHINNOSUKE;KIYONO HIROMI;MIYAGAKI MITSUHIRO;YOSHINO HIROSHI |
分类号 |
C07C249/16;C07B61/00;C07C251/76;C07C315/04;C07C317/18 |
主分类号 |
C07C249/16 |
代理机构 |
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