摘要 |
PROBLEM TO BE SOLVED: To provide a differentiation method for visually differentiating how a constituent is distributed in skin or transported therein at a damaged tight junction, the constituent being related to a skin barrier function caused by incompleteness in a tight junction function. SOLUTION: A tight junction damaged-skin model made by damage-treating a tight junction of a skin or a culture skin three-dimensional model and a fluorescence-labeled skin physiology-related component are used to visually differentiate how the function of the junction function is restored from a change in the distribution of the physiology-related component. COPYRIGHT: (C)2010,JPO&INPIT |