MARKERS OF OOCYTE VIABILITY

摘要

There is disclosed a method of determining the potential of individual oocyte to develop into a viable embryo, which method comprises establishing the concentration of any one or more of the markers identified in Table 2 in the follicular fluid of a single follicle from which said oocyte is derived and comparing the concentrations obtained to a reference concentration range that is established by comparing the concentration of said one or more markers from one or more follicles containing a fertilisation competent oocyte(s), wherein differential levels of said markers from said follicle to be tested compared to the reference range at least at the 5% significance level is predictive of a reduced potential of said oocyte to develop into a viable embryo following fertilisation.