发明名称 Salt forms of (2S)-(4E)-N-Methyl-5-[(5-Isopropoxy)pyridin-3-yl]-4-penten-2-amine
摘要 Orotic acid (uracil-6-carboxylic acid), R-mandelic acid and lysine monohydrochloride salt of (2S)-(4E)-N-methyl-5-[3-(5-isopropoxypyridin)yl]-4-penten-2-amine, and methods for their preparation, pharmaceutical compositions comprising said salts, and use, are disclosed. The salts can be administered to patients susceptible to or suffering from conditions and disorders, such as central nervous system disorders, to treat and/or prevent such disorders.
申请公布号 EP2133338(A1) 申请公布日期 2009.12.16
申请号 EP20090012024 申请日期 2007.05.08
申请人 ASTRAZENECA AB;TARGACEPT, INC. 发明人 BOHLIN, MARTIN HANS;DULL, GARY M.;ERIKSSON, CAROLINE;MILLER, CRAIG H;MUNOZ, JULIO A.;SEBHATU, TESFAI
分类号 A61P25/00;C07D213/65;A61K31/44 主分类号 A61P25/00
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