发明名称 |
Salt forms of (2S)-(4E)-N-Methyl-5-[(5-Isopropoxy)pyridin-3-yl]-4-penten-2-amine |
摘要 |
Orotic acid (uracil-6-carboxylic acid), R-mandelic acid and lysine monohydrochloride salt of (2S)-(4E)-N-methyl-5-[3-(5-isopropoxypyridin)yl]-4-penten-2-amine, and methods for their preparation, pharmaceutical compositions comprising said salts, and use, are disclosed. The salts can be administered to patients susceptible to or suffering from conditions and disorders, such as central nervous system disorders, to treat and/or prevent such disorders.
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申请公布号 |
EP2133338(A1) |
申请公布日期 |
2009.12.16 |
申请号 |
EP20090012024 |
申请日期 |
2007.05.08 |
申请人 |
ASTRAZENECA AB;TARGACEPT, INC. |
发明人 |
BOHLIN, MARTIN HANS;DULL, GARY M.;ERIKSSON, CAROLINE;MILLER, CRAIG H;MUNOZ, JULIO A.;SEBHATU, TESFAI |
分类号 |
A61P25/00;C07D213/65;A61K31/44 |
主分类号 |
A61P25/00 |
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