PREPARATION OF SUSTAINED RELEASE MEDICATION CONTAINING ALFUZOSIN HCL

摘要

PURPOSE: A sustained release containing alfuzosin HCl is provided to control drug release rate through control of kind and thickness of material and improve sustained release property. CONSTITUTION: A sustained release formulation containing alfuzosin comprises crystal core; a pharmacologically active ingredient layer containing alfuzosin HCl, water-insoluble polymer, water-soluble polymer or their mixture; a sustained release layer containing a sustained release film forming material; and a pharmaceutically active ingredient layer containing alfuzosin HCl and water-insoluble polymer, water-soluble polymer or their mixture.