| 发明名称 |
SUBSTITUTED ISOQUINOLINES AND THEIR USE AS RHO-KINASE INHIBITORS |
| 摘要 |
<p>The invention relates to 6-substituted isoquinoline and isoquinoline derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.</p> |
| 申请公布号 |
EP2132194(A2) |
申请公布日期 |
2009.12.16 |
| 申请号 |
EP20070856891 |
申请日期 |
2007.12.19 |
| 申请人 |
SANOFI-AVENTIS |
发明人 |
PLETTENBURG, OLIVER;LORENZ, KATRIN;GOERLITZER, JOCHEN;LOEHN, MATTHIAS |
| 分类号 |
C07D401/12;A61K31/4725;A61P3/00;A61P7/00;A61P9/00;A61P25/00;C07D401/14;C07D405/14;C07D451/06 |
主分类号 |
C07D401/12 |
| 代理机构 |
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代理人 |
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| 地址 |
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