发明名称 G-CSF DERIVATIVE FOR INDUCING IMMUNOLOGICAL TOLERANCE
摘要 The invention relates to a method for inducing immunological tolerance, in particular transplantation tolerance, by administering a G-CSF derivative or biologically active fragment, homolog, or variant thereof, in particular peg-G-CSF, to a donor cell or a transplantation donor. The invention also relates to expanding and stimulating selected donor cells by administering a G-CSF derivative, preferably peg-G-CSF. The donor cells are preferably granulocyte-monocyte precursor cells and IL-10 secreting T cells.
申请公布号 US2009304660(A1) 申请公布日期 2009.12.10
申请号 US20090544870 申请日期 2009.08.20
申请人 THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH 发明人 HILL GEOFFREY;MACDONALD KELLIE;MORRIS EDWARD
分类号 A61K35/12;A61K38/19;A61P37/06;C07K14/535;C12N5/02;C12N5/08;C12P21/04 主分类号 A61K35/12
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