发明名称 |
SMALLPOX DNA VACCINE AND THE ANTIGENS THEREIN THAT ELICIT AN IMMUNE RESPONSE |
摘要 |
The present invention relates to DNA vaccines that are capable of generating a protective immune response in mammals against a pox virus, and comprises at least one DNA plasmid capable of expressing a plurality of VACV MV antigens, and at least one DNA plasmid capable of expressing a plurality of VACV EV antigens. Also, the present invention relates to methods of inducing a protective immune response in a mammal to pox virus, including a neutralizing antibody response, comprising: injecting into tissue of said mammal said DNA vaccine.
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申请公布号 |
US2009304627(A1) |
申请公布日期 |
2009.12.10 |
申请号 |
US20090473634 |
申请日期 |
2009.05.28 |
申请人 |
VGX PHARMACEUTICALS, INC.;THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
DRAGHIA-AKLI RUXANDRA;PRIGGE JON;SARDESAI NIRANJAN Y.;WEINER DAVID B.;HIRAO LAUREN A. |
分类号 |
A61K39/275;A61K38/20;A61P31/20 |
主分类号 |
A61K39/275 |
代理机构 |
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代理人 |
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地址 |
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