发明名称 |
Single wall nanotube constructs and uses therefor |
摘要 |
The present invention provides soluble single wall nanotube constructs functionalized with a plurality of a targeting moiety and a plurality of one or more payload molecules attached thereto. The targeting moiety and the payload molecules may be attached to the soluble single wall carbon nanotube via a DNA or other oligomer platform attached to the single wall carbon nanotube. These soluble single wall carbon nanotube constructs may comprise a radionuclide or contrast agent and as such are effective as diagnostic and therapeutic agents. Methods provided herein are to diagnosing or locating a cancer, treating a cancer, eliciting an immune response against a cancer or delivering an anticancer drug in situ via an enzymatic nanofactory using the soluble single wall carbon nanotube constructs.
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申请公布号 |
US2009304581(A1) |
申请公布日期 |
2009.12.10 |
申请号 |
US20060989672 |
申请日期 |
2006.07.31 |
申请人 |
SCHEINBERG DAVID A;MCDEVITT MICHAEL;CHATTOPADHYAY DEBJIT;PHILIPS MARK REID |
发明人 |
SCHEINBERG DAVID A.;MCDEVITT MICHAEL;CHATTOPADHYAY DEBJIT;PHILIPS MARK REID |
分类号 |
A61K51/00;A61K38/08;A61K38/10;A61K38/16;A61K38/17 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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