摘要 |
The present invention provides a compound of formula (IV) wherein R is Cl, Br, NO2, OH or OR', and R' is alkyl, and its use in the synthesis of levocetirizine, including its use in the synthesis of (-)-1-[(4-chlorophenyl)-phenyl methyl] piperazine, an intermediate useful in the synthesis of levocetirizine. The present invention also provides compounds (II) and (III) which are useful in the synthesis of compound (IV). |
申请人 |
CIPLA LIMITED;RAO, DHARMARAJ RAMACHANDRA;KANKAN RAJENDRA NARAYANRAO;GHAGARE, MARUTI;CHIKHALIKAR, SANDIP VASANT;CURTIS, PHILIP, ANTHONY |
发明人 |
RAO, DHARMARAJ RAMACHANDRA;KANKAN RAJENDRA NARAYANRAO;GHAGARE, MARUTI;CHIKHALIKAR, SANDIP VASANT;CURTIS, PHILIP, ANTHONY |