CELL LINES THAT SECRETE SOLUBLE VEGF RECEPTORS AND USES THEREOF

摘要

The invention provides isolated nucleic acid and polypeptide sequences encoding Vascular Endothelial Growth Factor (VEGF) receptors, such as soluble VEGF receptors. Also encompassed are cell lines encoding such VEGF receptors. The invention also provides encapsulated cell therapy devices that are capable of delivering such VEGF receptors as well as methods of using these devices to deliver the VEGF receptors to the eye and to treat ophthalmic and cell proliferation disorders in patients suffering therefrom.