发明名称 METHOD OF MODELLING NEOVASCULARISATION OF DISK OF OPTIC NERVE
摘要 FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, namely to ophthalmology, and can be used in experimental ophthalmology for modelling neovascularisation of disk of optic nerve to enable estimate of effectiveness of antiangiogenic, antiinflammatory preparations. That is ensured by intravenous introduction of chlorine photosensitiser to a rabbit in a dose 2.5 mg/kg of weight. Ten minutes later disk of optic nerve is exposed to transpupillary laser irradiation. Power density is 200-250 J/cm2, lasing spot diametre is 6 mm. ^ EFFECT: method provides development of supplemental vessels of disk of optic nerve with pathological vascular wall, and also partial substitution of neural connective tissue.
申请公布号 RU2375759(C1) 申请公布日期 2009.12.10
申请号 RU20080132938 申请日期 2008.08.12
申请人 FEDERAL'NOE GOSUDARSTVENNOE UCHREZHDENIE "MEZHOTRASLEVOJ NAUCHNO-TEKHNICHESKIJ KOMPLEKS "MIKROKHIRURGIJA GLAZA" IM. AKADEMIKA S.N. FEDOROVA FEDERAL'NOGO AGENTSTVA PO VYSOKOTEKHNOLOGICHNOJ MEDITSINSKOJ POMOSHCHI" 发明人 BELYJ JURIJ ALEKSANDROVICH;TERESHCHENKO ALEKSANDR VLADIMIROVICH;VOLODIN PAVEL L'VOVICH;SOLOV'EV DMITRIJ KONSTANTINOVICH
分类号 A61N5/067;G09B23/28 主分类号 A61N5/067
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