| 摘要 |
<p num="1"><br/><br/>The present invention relates to a self-contained sensor controlled organ on a <br/>chip-device, which allows <br/>establishing or maintaining organs or organoids as well as stem cell niches in <br/>a miniaturized chip format, suitable for online observation by <br/>live cell imaging and for example two photon microscopy and their use for, <br/>e.g. testing the activity, pharmacodynamic and <br/>pharmacokinetic of compounds or to study self-assembly, homeostasis, damage, <br/>regeneration or interaction of organs or organoids and <br/>stem cell niches, as well as phenomena of maturation, aging, death and <br/>chronobiology.<br/> |
