Pharmaceutical Combination

摘要

Disclosed is a pharmaceutical combination comprising a calcium receptor modulator and a bone resorption inhibitor, wherein the calcium receptor modulator comprises a compound represented by the formula (I): wherein the ring A represents a 5- to 7-membered ring which may be substituted; the ring B represents a 5- to 7-membered heterocyclic ring which may be substituted; X1 represents CR1 (wherein R1 represents a hydrogen, a hydrocarbon group which may be substituted, or the like) or the like; X2 represents N or the like; Y represents C or the like; Ar represents a cyclic group which may be substituted; R represents a hydrocarbon group which may be substituted, or the like; and <img id="CUSTOM-CHARACTER-00001" he="2.79mm" wi="6.35mm" file="US20090304821A1-20091210-P00001.TIF" img-content="character" img-format="tif"/> represents a single bond or a double bond; or a salt thereof or a prodrug of the compound or the salt.