| 摘要 |
<p>The invention relates to water soluble binuclear cation nitrosyl complexes of iron with natural aliphatic thiolyls of general formula [Fe2(SR)2(NO)4]SO4, wherein R is natural sulphur-containing aliphatic ligands, preferably cysteamine or penicillamine, to a method for the production and the use thereof as an antitumoral medicinal agent, to a nitrogen monoxide donor based on said complexes, to tumor cell apoptosis inductor based thereon, to a pharmaceutical composition containing the above-mentioned complexes in an effective quantity and to a set applied for treating oncological diseases.</p> |
| 申请人 |
INSTITUTE OF PROBLEMS OF CHEMICAL PHYSICS RAS (IPCP RAS);SANINA, NATALIA ALEXEEVNA;LYSENKO, KONSTANTIN ALEXANDROVICH;ZHUKOVA, OLGA STEPANOVNA;RUDNEVA, TATYANA NIKOLAEVNA;EMELIANOVA, NINA SERGEEVNA;ALDOSHIN, SERGEI MIKHAILOVICH |
发明人 |
SANINA, NATALIA ALEXEEVNA;LYSENKO, KONSTANTIN ALEXANDROVICH;ZHUKOVA, OLGA STEPANOVNA;RUDNEVA, TATYANA NIKOLAEVNA;EMELIANOVA, NINA SERGEEVNA;ALDOSHIN, SERGEI MIKHAILOVICH |
