发明名称 USE OF TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF INFLAMMATORY PROCESSES
摘要 A method of treating inflammatory diseases of the airways or intestines which comprises administering substances selected from the group consisting of: (a) quinazolines of general formula wherein A, B, C, D, X, Ra, Rb, Rc and n are as defined herein, (b) the compounds (1) 4-[(3-chloro-4-fluorophenyl)amino]-6-[(4-dimethylamino-cyclohexyl)amino]-pyrimido[5,4-d]pyrimidine, (2) 4-[(R)-(1-phenylethyl)amino]-6-(4-hydroxyphenyl)-7H-pyrrolo[2,3-d]pyrimidine, and (3) 4-{[3-chloro-4-(3-fluoro-4-benzyloxy)-phenyl]amino}-6-(5-{[(2-methanesulphonyl-ethyl)amino]methyl}-furan-2-yl)quinazoline or (d) the antibodies Cetuximab C225, Trastuzumab, ABX-EGF and Mab ICR-62, and (f) EGFR-antisense.
申请公布号 US2009306072(A1) 申请公布日期 2009.12.10
申请号 US20090543984 申请日期 2009.08.19
申请人 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG 发明人 JUNG BIRGIT;PUESCHNER HUBERT
分类号 A61K31/517;C07D239/94;A61K31/4709;A61K31/506;A61K31/519;A61K31/52;A61K31/5377;A61K31/55;A61K31/7088;A61K39/395;A61P1/04;A61P11/00;A61P11/06;A61P29/00;C07D405/14;C07D413/12 主分类号 A61K31/517
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