发明名称 |
SOLID SOLUTION BEADLET |
摘要 |
Disclosed is a beadlet comprising (i) a hydrophobic long chain fatty acid or ester material; (ii) a surfactant; and (iii) a therapeutic agent, which in admixture form a solid solution at room temperature. The hydrophobic material preferably has a melting point of about 40 to about 100 .degree.C, and is most preferably glyceryl behenate. The surfactant is preferably a polyglycolyzed glyceride, polyoxyethylene sorbate, ethylene or propylene block copolymer or combinations thereof, and is most preferably polyoxyethylene 20 sorbitan monolaurate.
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申请公布号 |
CA2302275(C) |
申请公布日期 |
2009.12.08 |
申请号 |
CA19982302275 |
申请日期 |
1998.09.18 |
申请人 |
SHIRE LABORATORIES, INC. |
发明人 |
MC GUINNESS, CHARLOTTE M.;RUDNIC, EDWARD M.;GUO, XIAODI;BURNSIDE, BETH A.;COUCH, RICHARD A.;TUSTIAN, ALEXANDER K. |
分类号 |
A61K9/00;A61K9/14;A61K9/16;A61K9/20;A61K9/50;A61K31/4458;A61K31/4985;A61K31/522;A61K38/09;A61K38/11;A61K38/21;A61K38/22;A61K45/06;A61K47/06;A61P25/06;A61P31/12 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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