发明名称 Composition and corresponding method of using spores of Bacillus subtilis to stimulate and/or enhance immune response in mammals
摘要 Disclosed is a composition for administration to a human or animal subject, the composition containing spores of Bacillus subtilis in an amount effective to stimulate immune responsiveness in the subject. The spores have an adjuvant, immunomodulatory, immune potentiation, or dendritic cell maturation effect, or a combination thereof Also disclosed is a method of boosting an immune response in an animal subject by administering B. subtilis spores to an animal or human subject. Further disclosed is a vaccine containing B. subtilis spores, in the presence or absence of an antigen.
申请公布号 US7628982(B2) 申请公布日期 2009.12.08
申请号 US20020309635 申请日期 2002.12.04
申请人 KING'S COLLEGE LONDON 发明人 KLAVINISKIS LINDA SYLVIA;BARNES ANDREW GRAHAM COLIN
分类号 A01N63/00;A01N65/00;A61K35/74;A61K39/07;A61K39/08;A61K39/38;A61K39/39;A61K45/00;A61K48/00;A61P37/00 主分类号 A01N63/00
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