| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method of producing 4-[3-isopropyl-5-(6-phenylpyridin-3-yl)-4H-1,2,4-triazol-4-yl]-2,1,3-benzoxadiazole or its salt useful as a medicine, particularly as a glycine-transporter inhibiting agent, more specifically, for example, as a therapeutic agent and/or a prophylactic agent for dementia or schizophrenia, or in a certain aspect, for a central nervous system disorder or the like such as dementia or schizophrenia associated with Alzheimer's disease. Ž<P>SOLUTION: The method of producing 4-[3-isopropyl-5-(6-phenylpyridin-3-yl)-4H-1,2,4-triazol-4-yl]-2,1,3-benzoxadiazole or its salt is characterized in that N-2,1,3-benzoxadiazol-4-yl-6-phenylnicotineamide is an intermediate therefor. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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