<p>It has been found that nonimmunosuppressive, cyclophilin-binding cyclosporins are useful in the treatment and prevention of AIDS and AIDS-related disorders. Such cyclosporins include novel Ciclosporin derivatives modified at the 4- and/or 5-positions.</p>
申请公布号
EP0484281(B1)
申请公布日期
1997.01.29
申请号
EP19910810841
申请日期
1991.10.30
申请人
SANDOZ-PATENT-GMBH
发明人
KO, SOO YOUNG;KOBEL, HANS;ROSENWIRTH, BRIGITTE;SEEBACH, DIETER;TRABER, RENE P.;WENGER, ROLAND;BOLLINGER, PIETRO