发明名称 |
PROCESS FOR PRODUCING OSELTAMIVIR PHOSPHATE AND INTERMEDIATE COMPOUND |
摘要 |
<p>Disclosed are a process suited to large scale synthesis with high yield for producing oseltamivir phosphate, in which a preparation of oseltamivir phosphate which is highly safe as a pharmaceutical product can be produced, and an intermediate compound for producing oseltamivir phosphate. In this production process, an intermediate compound represented by general formula (V) is synthesized by employing Michael reaction/Michael reaction/Horner-Wadsworth-Emmons reaction, and oseltamivir phosphate is produced by converting the substituent groups in this intermediate compound.</p> |
申请公布号 |
WO2009145263(A1) |
申请公布日期 |
2009.12.03 |
申请号 |
WO2009JP59789 |
申请日期 |
2009.05.28 |
申请人 |
TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION;HAYASHI, YUJIRO;ISHIKAWA, HAYATO |
发明人 |
HAYASHI, YUJIRO;ISHIKAWA, HAYATO |
分类号 |
C07C231/10;C07C47/198;C07C205/55;C07C233/52;C07C233/91;C07C247/22;C07C263/12;C07C265/10;C07C319/18;C07C323/61;C07D209/48 |
主分类号 |
C07C231/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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