发明名称 |
ANTI-HIV VACCINES CONSTRUCTED BASED ON AMINO ACID MUTATION OF ATTENUATED LIVE VACCINE OF EIAV |
摘要 |
<p>Provided are antigenic polypeptides of HIV envelope glycoproteins which are constructed based on amino acid mutation of attenuated live vaccine of Equine Infectious Anemia Virus, DNA constructions and recombinant virus vectors comprising polynucleotides encoding said polypeptides, antibodies against said polypeptides as well as uses thereof in preventing and treating HIV infection. Said antigenic polypeptides and vaccines can induce high titer neutralization antibodies against HIV in organism.</p> |
申请公布号 |
WO2009143775(A1) |
申请公布日期 |
2009.12.03 |
申请号 |
WO2009CN72017 |
申请日期 |
2009.05.27 |
申请人 |
NATIONAL CENTER FOR AIDS/STD CONTROL AND PREVENTION, CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION;SHAO, YIMING;LIU, LIANXING;SHEN, RONGXIAN |
发明人 |
SHAO, YIMING;LIU, LIANXING;SHEN, RONGXIAN |
分类号 |
C07K14/16;A61K38/16;A61K39/21;A61P31/18;C07H21/02;C07K14/155;C07K16/10;C12N15/86;C12N15/861;C12N15/863;C12N15/867;C12N15/869;C12R1/93 |
主分类号 |
C07K14/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|