发明名称 |
METHOD FOR PRODUCING VESICLE, VESICLE OBTAINED BY THE METHOD AND W/O/W EMULSION FOR PRODUCING VESICLE |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for producing a vesicle, which simultaneously achieves a high inclusion rate of active ingredient and control of particle diameter. <P>SOLUTION: The vesicle is produced by a process for producing a W/O emulsion from an aqueous solution containing a substance to be included in a dissolved or suspended state and an organic solvent phase containing a lipid having an emulsification ability of constituting a vesicle, a process for producing a W/O/W emulsion from the above W/O emulsion and an external water-phase solution of a water-soluble emulsifying agent not breaking a vesicle lipid membrane and a process for removing the organic solvent phase from the W/O/W emulsion to form a vesicle. <P>COPYRIGHT: (C)2010,JPO&INPIT |
申请公布号 |
JP2009280525(A) |
申请公布日期 |
2009.12.03 |
申请号 |
JP20080135009 |
申请日期 |
2008.05.23 |
申请人 |
UNIV OF TSUKUBA |
发明人 |
ICHIKAWA SOSAKU;KUROIWA TAKASHI |
分类号 |
A61K9/127;A61K8/06;A61K8/14;A61K9/113;A61Q19/00;B01J13/00;B01J13/12 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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