发明名称 METHOD FOR PRODUCING VESICLE, VESICLE OBTAINED BY THE METHOD AND W/O/W EMULSION FOR PRODUCING VESICLE
摘要 <P>PROBLEM TO BE SOLVED: To provide a method for producing a vesicle, which simultaneously achieves a high inclusion rate of active ingredient and control of particle diameter. <P>SOLUTION: The vesicle is produced by a process for producing a W/O emulsion from an aqueous solution containing a substance to be included in a dissolved or suspended state and an organic solvent phase containing a lipid having an emulsification ability of constituting a vesicle, a process for producing a W/O/W emulsion from the above W/O emulsion and an external water-phase solution of a water-soluble emulsifying agent not breaking a vesicle lipid membrane and a process for removing the organic solvent phase from the W/O/W emulsion to form a vesicle. <P>COPYRIGHT: (C)2010,JPO&INPIT
申请公布号 JP2009280525(A) 申请公布日期 2009.12.03
申请号 JP20080135009 申请日期 2008.05.23
申请人 UNIV OF TSUKUBA 发明人 ICHIKAWA SOSAKU;KUROIWA TAKASHI
分类号 A61K9/127;A61K8/06;A61K8/14;A61K9/113;A61Q19/00;B01J13/00;B01J13/12 主分类号 A61K9/127
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