发明名称 BCMA POLYPEPTIDES AND USES THEREOF
摘要 The present invention relates to polypeptides that inhibit APRIL and/or BAFF binding to BCMA, nucleic acid molecules encoding the polypeptides, and compositions comprising the polypeptides. The present invention also relates to methods for treating an immune-related disease or cancer using the polypeptides and compositions of the invention. The present invention also relates to methods for identifying inhibitors of APRIL/BAFF binding to BCMA and APRIL/BAFF signaling.
申请公布号 US2009297504(A1) 申请公布日期 2009.12.03
申请号 US20090405018 申请日期 2009.03.16
申请人 GENENTECH, INC. 发明人 KELLEY ROBERT F.;PATEL DARSHANA RAMESH
分类号 A61K39/395;A61K38/00;A61P35/00;A61P37/00;C07H21/04;C07K14/705;C07K16/00;C12N5/10;C12N15/63;C12P21/02;G01N33/53 主分类号 A61K39/395
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