| 摘要 |
Self-sealing assemblies and methods of establishing a fluid-seal around a medical instrument are disclosed herein. An assembly for providing resistance to fluid leakage includes an introducer section having a mouth portion, a stem portion, and a longitudinal axis therebetween, wherein a diameter of the mouth portion decreases over a length of the mouth portion, and wherein a diameter of the stem portion remains substantially the same over a length of the stem portion; a transfer section having a proximal end and a distal end; and a self-sealing membrane at a junction between the stem portion and the proximal end of the transfer section, wherein the self-sealing membrane is composed of a single piece flexible elastomeric material, and wherein the diameter and the length of the stem portion and a thickness and a diameter of the self-sealing membrane provide structural integrity to the assembly resulting in the ability of the self-sealing membrane to resist fluid leakage prior to, during, and after the self-sealing membrane is punctured.
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