| 发明名称 |
HUMAN BIOMARKERS FOR DETERMINING INTRINSIC B-CELL DEFECTS |
| 摘要 |
Human biomarkers (i.e., E47, AID or IgH that has undergone class switching) are described that characterize the immune potential of B lymphocytes, which produce immunoglobulins (Ig), and their ability to respond to infections by a pathogen or a vaccine. A reduction in one, any two or all three may be diagnostic of an intrinsic B-cell defect in a humoral immune response.
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| 申请公布号 |
WO2009105275(A3) |
申请公布日期 |
2009.12.03 |
| 申请号 |
WO2009US01131 |
申请日期 |
2009.02.23 |
| 申请人 |
THE UNIVERSITY OF MIAMI;BLOMBERG, BONNIE, B.;FRASCA, DANIELA;KENYON, NORMA |
发明人 |
BLOMBERG, BONNIE, B.;FRASCA, DANIELA;KENYON, NORMA |
| 分类号 |
G01N33/53;A61K39/00;G01N33/68 |
主分类号 |
G01N33/53 |
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