ASSAY FOR MEASUREMENT OF APURINIC/APYRIMIDINIC (AP) SITES AND FOR SCREENING AP-SITE REACTIVE COMPOUNDS

摘要

A method of detecting abasic (AP) sites in DNA from a subject includes isolating a sample of DNA from a subject under examination, contacting the DNA with a fluorescent aldehyde reactive probe (FARP), and detecting FARP labeled AP sites in the DNA sample.