发明名称 |
Method for Treating Ocular Cancer |
摘要 |
It has now been found that the p53 pathway is inactivated in ocular cancers such as retinoblastoma. As such, the present invention is a method for inducing ocular cancer cell death using a p53 activator. In particular embodiments, the p53 activator blocks the interaction between DM2 or DMX and p53. As the p53 activator induces ocular cancer cell death, a method for preventing or treating ocular cancer is also provided.
|
申请公布号 |
US2009298785(A1) |
申请公布日期 |
2009.12.03 |
申请号 |
US20070373308 |
申请日期 |
2007.07.24 |
申请人 |
DYER MICHAEL A;MARINE JEAN-CHRISTOPHE;JOCHEMSEN AART GERRIT |
发明人 |
DYER MICHAEL A.;MARINE JEAN-CHRISTOPHE;JOCHEMSEN AART GERRIT |
分类号 |
A61K31/704;A61K31/18;A61K31/4164;A61K31/4375;A61K31/496;A61K31/551;A61K31/5513;A61K31/7064;A61P35/00;C12N5/06 |
主分类号 |
A61K31/704 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|