PROCESSES FOR THE PREPARATION AND PURIFICATION OF PALIPERIDONE PALMITATE
摘要
The present invention encompasses processes for the preparation and purification of paliperidone palmitate, for the purification of palmitic acid, for the preparation of paliperidone sodium salt and the preparation of paliperidone tetradecanoate or octadecanoate ester. The latter may further be used in a quantification method for determining the purity of paliperidone palmitate.
申请公布号
WO2009089076(A3)
申请公布日期
2009.12.03
申请号
WO2009US00205
申请日期
2009.01.12
申请人
TEVA PHARMACEUTICAL INDUSTRIES LTD.;TEVA PHARMACEUTICALS USA, INC.;INI, SANTIAGO;SHMUELY, YARON;PORTER-KLEKS, OSNAT;CHEN, KOBI;LANCRY, ELI;SINGER, CLAUDE
发明人
INI, SANTIAGO;SHMUELY, YARON;PORTER-KLEKS, OSNAT;CHEN, KOBI;LANCRY, ELI;SINGER, CLAUDE