发明名称 POLYSUBSTITUTED DERIVATIVES OF 2-ARYL-6-PHENYL-IMIDAZO[L,2- ?] PYRIDINES, AND PREPARATION AND THERAPEUTIC USE THEREOF
摘要 <p>Compounds of Formula (I): (I) ooo phenyl group or a naphthyl group, optionally substituted for one or a plurality of atoms or groups; X is 1 to 4 substituents, identical to or different from each other and selected from halogen, (C1-C10)alkyl, halo(C1-C10)alkyl, (C1-C10)alcoxy, NRaRb, cyano, or nitro, the (C1-C10)alkyl capable of being substituted for halogen or an NRaRb or hydroxyl group; R2 and R3, independently of each other, represent a hydrogen atom or a (C1-C10)alkyl group, this group being optionally substituted for an Rf group; an aryl group, the aryl being optionally substituted for one or a plurality of substituents selected from halogen or a (C1-C10)alkyl, halo(C1-C10)alkyl, (C1-C10)alcoxy, halo(C1-C10)alcoxy, NRaRb, hydroxyl, nitro, or cyano group; R2 and X may form, together with the carbon atoms carrying them, a carbon ring of 5 to 7 carbon atoms; R4 is a hydrogen atom, a (C1-C10)alkyl group optionally substituted for an Rf group, or an aryl group optionally substituted as a base or salt having an acid added. The invention is used in therapy and in synthesis methods.</p>
申请公布号 WO2009144391(A1) 申请公布日期 2009.12.03
申请号 WO2009FR00297 申请日期 2009.03.20
申请人 SANOFI-AVENTIS;DE PERETTI, DANIELLE;EVANNO, YANNICK 发明人 DE PERETTI, DANIELLE;EVANNO, YANNICK
分类号 C07D471/04;A61K31/437;A61P19/00;A61P25/00;A61P35/00;C07D213/28;C07D233/56 主分类号 C07D471/04
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