发明名称 |
COMPOUNDS COMPRISING A 3-PYRIDINOL OR 5-PYRIMIDINOL RING HAVING AN ORGANOSELENO OR ORGANOTELLURO SUBSTITUENT FOR USE AS ANTIOXIDANTS |
摘要 |
<p>Compounds comprising a 3-pyridinol or 5-pyrimidinol ring carrying an organoseleno- or organotelluro- substituent on the pyridine or pyrimidine ring, exhibit useful antioxidant properties. The compounds may for example be in accordance with the following formula (I) as defined herein. Catalytic chain-breaking and hydroperoxide decomposing antioxidant properties are also disclosed. Furthermore the compounds may be used in combination with a reducing agent. The compounds are useful for the stabilization of man-made and natural materials, or for the prevention or treatment of disorders caused by or involving free radical-mediated or oxidative tissue damage.</p> |
申请公布号 |
WO2009144253(A1) |
申请公布日期 |
2009.12.03 |
申请号 |
WO2009EP56468 |
申请日期 |
2009.05.27 |
申请人 |
KAROLINSKA INSTITUTET INNOVATIONS AB;ENGMAN, LARS |
发明人 |
ENGMAN, LARS |
分类号 |
A61K31/44;A61K31/505;A61P39/06;C07D213/60;C09K15/32 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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