发明名称 |
CXCR3 CHEMOKINE RECEPTOR, ANTIBODY, NUCLEIC ACID AND METHOD OF USE |
摘要 |
PROBLEM TO BE SOLVED: To provide a method of use for characterizing one or a plurality of ligands of an orphan receptor. SOLUTION: A method for inhibiting binding of a ligand selected from the group consisting of IP-10 and Mig to human CXC chemokine receptor 3 (CXCR3) protein is provided. The method includes a process for bringing the CXCR3 protein to contact with an antibody bonded to the CXC chemokine receptor 3 (CXCR3) protein having a pecific amino acid sequence, or an antigen-binding fragment. COPYRIGHT: (C)2010,JPO&INPIT |
申请公布号 |
JP2009278990(A) |
申请公布日期 |
2009.12.03 |
申请号 |
JP20090167709 |
申请日期 |
2009.07.16 |
申请人 |
THEODOR-KOCHER INST;MILLENNIUM PHARMACEUTICALS INC |
发明人 |
LOETSCHER MARCEL;MOSER BERNHARD;QIN SHIXIN;MACKAY CHARLES R |
分类号 |
C12Q1/02;A61K38/00;A61K39/395;A61K47/48;A61P31/00;A61P35/00;A61P37/00;A61P37/06;A61P43/00;C07K14/715;C12N15/09;C12N15/12 |
主分类号 |
C12Q1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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