CELL SEPARATION DEVICE. CELL SEPARATION SYSTEM AND CELL SEPARATION METHOD

摘要

Disclosed is a cell separation device, cell separation system and cell separation method capable of continuous treatment without binding fluorescent particles or magnetic particles to the surface of the cell membrane, wherein, when a sample cell suspension containing the desired target cells is supplied continuously from a sample inlet (12) and physiological saline is supplied continuously from a physiological saline inlet (14), the sample cell suspension flows together with the physiological saline in a liquid flow path (10) and an adsorption force acts on the target cells due to affinity bonding from the adsorbing portions of adsorbing regions (22) in the form of strips formed in a planar wall portion (20). Because the adsorbing regions (22) in the form of strips lie asymmetrically with respect to the direction of the liquid flow path (10), the adsorption force acting on the target cells has a component perpendicular to the direction of the flow path. As a result, as shown in Figure 1, after flowing for a given distance in the liquid flow path (10) the target cells collect on one side of the planar wall portion (20), and can be separated continuously from the non-target constituents.