| 摘要 |
PROBLEM TO BE SOLVED: To provide an agent capable of not only decreasing dosage in pharmaceutical compositions, but also, especially, uniforming oral absorption regardless of food conditions and giving uniform therapeutic response on all patients in administration of 1-[2-(2-naphthyl)-ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride. SOLUTION: A pharmaceutical composition containing 1-[2-(2-naphthyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride as a microparticulate form comprising particles whose at least 55% population has a diameter of 50μm or less, is provided. COPYRIGHT: (C)2010,JPO&INPIT
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