发明名称 GADOLINIUM COMPOUND AND CONTRAST MEDIUM FOR MRI
摘要 PROBLEM TO BE SOLVED: To provide a new gadolinium compound having high T1 relaxation ability, enabling imaging in high sensitivity only by small dosage, exhibiting excellent imaging of the systemic blood vessel and the liver, and having the safety of enabling a large amount thereof to be excreted to the outside of the body within 24 hr, and to provide a contrast medium for MRI, containing the compound. SOLUTION: The gadolinium compound is a gadolinium complex such as Glu-4Ac-Gd-DTPA, Glu-4-Gd-DTPA-6 and Glu-4-Gd-DTPA-3 (wherein, Glu is glucose; Ac is acetyl; and DTPA is diethylenetriaminepentaacetic acid). The contrast medium for the MRI contains the complex or the like. COPYRIGHT: (C)2010,JPO&INPIT
申请公布号 JP2009280540(A) 申请公布日期 2009.12.03
申请号 JP20080136139 申请日期 2008.05.26
申请人 KONICA MINOLTA HOLDINGS INC;NATIONAL UNIV CORP SHIZUOKA UNIV;HAMAMATSU UNIV SCHOOL OF MEDICINE 发明人 MIURA AKIO;YAMASHITA KOJI;SAKAHARA HARUMI;TAKEHARA YASUO;FUJIE MICHIO;AOKI SHUN
分类号 C07C237/10;A61K49/00;C07C237/08;C07F5/00;C07H15/12 主分类号 C07C237/10
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