发明名称 Impurities of Donepezil
摘要 The present invention relates to impurities of donepezil, or a pharmaceutically acceptable salt thereof, which may be produced during synthesis and storage of donepezil, or a pharmaceutically-acceptable salt thereof, and to methods of identifying such impurities. The invention also relates to the use of these impurities in analytical techniques and to product that contain certain low levels of these impurities in particular the following impurities are disclosed: formula (I) and formula (II).
申请公布号 US2009298879(A1) 申请公布日期 2009.12.03
申请号 US20070301396 申请日期 2007.05.18
申请人 PLIVA HRVATSKA D.O.O. 发明人 KRIZMANIC IRENA;LERMAN LIDIJA;SAMARDZIC ZRINKA;KACZOROWSKA KATARZYNA;MANIKOWSKI ANDRZEJ;ZIORO BARBARA;GREBENAR IVICA;KORUZNJAK JASNA DOGAN
分类号 A61K31/445;A61P25/00;C07C211/01;C07D211/06;G01N30/02 主分类号 A61K31/445
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