BINDING AGENTS DIRECTED AGAINST IL-4 RECEPTOR FOR THE TREATMENT OF TUMORS, INFLAMMATORY AND IMMUNOLOGICAL DISORDERS
摘要
The present invention relates to the use of an antigen-binding agent directed against human interleukin-4 receptor for the prevention and/or treatment of tumors, inflammatory and immunological disorders. Further the invention relates to methods of inhibiting the bioactivity of IL-4 without inhibiting binding of IL-4 to IL-4R and particularly to methods for treatment and/or prevention of tumors, inflammatory and immunological disorders, the methods comprising administering to an individual in need thereof an antigen-binding agent with binding affinity for IL-4R.
申请公布号
WO2009121847(A3)
申请公布日期
2009.12.03
申请号
WO2009EP53756
申请日期
2009.03.30
申请人
APOGENIX GMBH;HILL, OLIVER;BRANSCHAEDEL, MARCUS;GIEFFERS, CHRISTIAN;THIEMANN, MEINOLF;MERZ, CHRISTIAN
发明人
HILL, OLIVER;BRANSCHAEDEL, MARCUS;GIEFFERS, CHRISTIAN;THIEMANN, MEINOLF;MERZ, CHRISTIAN