| 摘要 |
[PROBLEMS] To provide: a polysulfone-based membrane for treating blood which is excellent in antioxidant properties and storage stability over a long time, has a high practical strength and can be highly conveniently produced; a polysulfone-based membrane for treating blood which is excellent in antioxidant properties and storage stability over a long time, suffers from little risk of contamination of the liquid to be treated with an endotoxin, has a high practical strength and can be highly conveniently produced; and a method of producing the same. [MEANS FOR SOLVING PROBLEMS] A polysulfone-based membrane for treating blood which comprises a polysulfone-based resin, a hydrophilic polymer and a fat-soluble antioxidant agent, characterized in that the membrane contains from 30 to 76 mg of the fat-soluble antioxidant agent per gram of the membrane and the total amount of the fat-soluble antioxidant agent present on the membrane surface is from 4 to 25 mg per gram of the membrane; a polysulfone-based membrane for treating blood which is further characterized in that the membrane contains from 30 to 76 mg of the fat-soluble antioxidant agent per gram of the membrane and the TOF-SIMS standard peak strength of the fat-soluble antioxidant agent is 1.8x10or more on the inner surface of the membrane and 2.4x10or more on the outer surface of the membrane; and a method of producing a membrane for treating blood which comprises a polysulfone-based resin, a hydrophilic polymer and a fat-soluble antioxidant agent, characterized by comprising preparing an intermediate membrane containing from 30 to 76 mg of a fat-soluble antioxidant agent per gram of the membrane and then heating the intermediate membrane in a dry state at 100 to 180C for 0.1 to 360 minutes.
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