发明名称 |
Transactivation method of regulating foreign gene expression |
摘要 |
The present invention provides a process and host cell for use in increasing the amount of a desired protein produced by a cell line. The process and the cell line use a first transcription unit containing a gene for a transactivator protein to control the transactivation of a second transcription unit such that the amount of desired protein expression can be increased without affecting adversely cell growth. Preferred transactivator proteins are derived from E1A.
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申请公布号 |
US5866359(A) |
申请公布日期 |
1999.02.02 |
申请号 |
US19950442646 |
申请日期 |
1995.05.16 |
申请人 |
ALUSUISSE HOLDINGS A.G. |
发明人 |
COCKETT, MARK IAN;BEBBINGTON, CHRISTOPHER ROBERT;YARRANTON, GEOFFREY THOMAS |
分类号 |
C12N15/09;C12N5/10;C12N15/85;C12P21/00;C12R1/91;C12R1/92;(IPC1-7):C12N5/10 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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