| 发明名称 |
NAPHTHALENE AND QUINOLINE SULFONYLUREA DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS |
| 摘要 |
<p>The invention is directed to naphthalene and quinoline sulfonylurea derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis and cancer. Pharmaceutical compositions and methods of use are also included.</p> |
| 申请公布号 |
EP2125724(A1) |
申请公布日期 |
2009.12.02 |
| 申请号 |
EP20080733664 |
申请日期 |
2008.03.25 |
| 申请人 |
MERCK FROSST CANADA LTD. |
发明人 |
BURCH, JASON;FARAND, JULIE;HAN, YONGXIN;STURINO, CLAUDIO |
| 分类号 |
C07D209/64;A61K31/4035;A61K31/4745;C07D471/04 |
主分类号 |
C07D209/64 |
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