发明名称 PHENYLAZOLE COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND DRUGS FOR HYPERLIPEMIA
摘要 Phenylazole compounds represented by general formula (1) or pharmaceutically acceptable salts thereof and drugs for hyperlipemia which contain these compounds as the active ingredient, wherein A represents imidazolyl, pyrazolyl, etc.; B represents (1a) or (1b) (wherein R<2> and R<3> represent each hydrogen, C1-6 alkyl, etc.; and k is 0 or an integer of 1 to 15); Y represents O, S, a bond, etc.; and Z represents an optionally substituted and saturated or unsaturated heterocycle containing 1 to 4 N, O or S atoms. Among all, compounds wherein Z is substituted chroman-2-yl, 2,3-dihydrobenzofuran-2-yl, etc. have an effect of inhibiting the formation of lipid peroxides too.
申请公布号 WO0006550(A1) 申请公布日期 2000.02.10
申请号 WO1999JP04070 申请日期 1999.07.29
申请人 NIPPON SODA CO., LTD.;UMEDA, NOBUHIRO;MOCHIZUKI, NOBUO;UCHIDA, SEIICHI;NISHIBE, TADAYUKI;YAMADA, HIROKAZU;ITO, KUNIHITO;HORIKOSHI, HIROMI 发明人 UMEDA, NOBUHIRO;MOCHIZUKI, NOBUO;UCHIDA, SEIICHI;NISHIBE, TADAYUKI;YAMADA, HIROKAZU;ITO, KUNIHITO;HORIKOSHI, HIROMI
分类号 A61P1/16;C07D231/12;C07D233/58;C07D233/61;C07D405/12;C07D491/048;C07D491/052;C07D521/00;(IPC1-7):C07D231/12;C07D401/12;C07D403/12;C07D409/12;C07D413/12;C07D417/12;C07D473/28;A61K31/415;A61K31/42;A61K31/425;A61K31/44;A61K31/47;A61K31/495;A61K31/505;A61K31/52;A61K31/535 主分类号 A61P1/16
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