发明名称 |
PHENYLAZOLE COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND DRUGS FOR HYPERLIPEMIA |
摘要 |
Phenylazole compounds represented by general formula (1) or pharmaceutically acceptable salts thereof and drugs for hyperlipemia which contain these compounds as the active ingredient, wherein A represents imidazolyl, pyrazolyl, etc.; B represents (1a) or (1b) (wherein R<2> and R<3> represent each hydrogen, C1-6 alkyl, etc.; and k is 0 or an integer of 1 to 15); Y represents O, S, a bond, etc.; and Z represents an optionally substituted and saturated or unsaturated heterocycle containing 1 to 4 N, O or S atoms. Among all, compounds wherein Z is substituted chroman-2-yl, 2,3-dihydrobenzofuran-2-yl, etc. have an effect of inhibiting the formation of lipid peroxides too.
|
申请公布号 |
WO0006550(A1) |
申请公布日期 |
2000.02.10 |
申请号 |
WO1999JP04070 |
申请日期 |
1999.07.29 |
申请人 |
NIPPON SODA CO., LTD.;UMEDA, NOBUHIRO;MOCHIZUKI, NOBUO;UCHIDA, SEIICHI;NISHIBE, TADAYUKI;YAMADA, HIROKAZU;ITO, KUNIHITO;HORIKOSHI, HIROMI |
发明人 |
UMEDA, NOBUHIRO;MOCHIZUKI, NOBUO;UCHIDA, SEIICHI;NISHIBE, TADAYUKI;YAMADA, HIROKAZU;ITO, KUNIHITO;HORIKOSHI, HIROMI |
分类号 |
A61P1/16;C07D231/12;C07D233/58;C07D233/61;C07D405/12;C07D491/048;C07D491/052;C07D521/00;(IPC1-7):C07D231/12;C07D401/12;C07D403/12;C07D409/12;C07D413/12;C07D417/12;C07D473/28;A61K31/415;A61K31/42;A61K31/425;A61K31/44;A61K31/47;A61K31/495;A61K31/505;A61K31/52;A61K31/535 |
主分类号 |
A61P1/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|