发明名称 |
High purity butoconazole nitrate with specified particle size and a process for the preparation thereof |
摘要 |
One object of the invention is high purity butoconazole nitrate of the formula (I) (I) containing maximum 0.1 wt % of chemical impurities, wherein at least 95% of the particles of the substance are below 75 mum by diameter, whereas at least 99% of the particles are below 250 mum by diameter, and process for its preparation. A pharmaceutical composition comprising as active ingredient, high purity butoconazole nitrate of specified particle size in admixture with known auxiliaries is also within the scope of the invention.
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申请公布号 |
US7625935(B2) |
申请公布日期 |
2009.12.01 |
申请号 |
US20050584662 |
申请日期 |
2005.01.25 |
申请人 |
RICHTER GEDEON VEGYESZETI GYAR RT. |
发明人 |
CZIBULA LASZLO;DOBAY LASZLO;WERKNE PAPP EVA;NAGYNE BAGDY JUDIT;SEBOK FERENC |
分类号 |
A61K31/4174;C07D233/54;C07D233/56;C07D233/60 |
主分类号 |
A61K31/4174 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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