发明名称 PHARMACEUTICAL COMPOSITIONS COMPRISING IRON CHELATORS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS AND SOME NOVEL IRON CHELATORS
摘要 Use of a compound of formula II: (see above formula) wherein R4 is (C1-C6)acyl, nitro(C1-C6)alkyl, cyano(C1-C6) alkyl, (C1--C6)alkoxy(Cl-C6)alkyl or -CH2NR7R8, wherein R7 and R8, the same or different, is each H or (C1-C6)alkyl, or together with the N atom form a saturated or unsaturated 5- 7 membered ring optionally containing a further heteroatom being N, O or S, the further N atom being optionally substituted, and either R5 is H and R6 is (C2-C6) acyl or hydroxyimino (C2--C6)alkyl, or R5 and R6 together with the phenyl ring form a quinoline, a 1,2,3,4-- tetrahydroquinoline or a perhydroquinoline ring, for the preparati on of pharmaceutically compositions for the treatment of Parkinson's disease or stroke.
申请公布号 CA2374317(C) 申请公布日期 2009.12.01
申请号 CA20002374317 申请日期 2000.06.07
申请人 YEDA RESEARCH AND DEVELOPMENT CO. LTD.;TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. 发明人 WARSHAWSKY, ABRAHAM;YOUDIM, MOUSSA B. H.;BEN-SHACHAR, DORIT
分类号 C07D401/10;A61K31/165;A61K31/225;A61K31/27;A61K31/47;A61K31/4709;A61K31/495;A61K31/496;A61K31/5377;A61K31/551;A61P25/16 主分类号 C07D401/10
代理机构 代理人
主权项
地址